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Informer pasient om forventede seponerings- og abstinensreaksjoner: Intensitet og forekomst av symptomer varierer mellom pasienter og er avhengig av inntatt dose, varighet av bruken og hvor raskt nedtrappingen skjer.De syntetiske opioider petidin og fentanyl virker på de samme modtagere i nervesystemet som morfin, og de ligner morfin i deres virkn